Here is everything you need to know about the games including betting tips, odds, and predictions for the best bets tonight.
Real Sociedad Vs Roma
Currently winless in their last five games with three draws and two losses, Real Sociedad will face an uphill to overturn a two-goal deficit tonight.
The White-blues were beaten 2-0 in the first leg, and have now won just one of their seven matches against Italian sides in European competition (D2 L4).
Roma have progressed from all five of their previous two-legged ties in the knockout stages of the UEFA Europa League after winning the first leg, with one of those being a 4-1 aggregate victory over Spanish side Villarreal in 2016-17.
BETTING TIP: Roma wins and 0-2 goals in the match.
ODDS: 6.00
Arsenal Vs Sporting CP
This will be the sixth meeting between Arsenal and Sporting CP in the European competition.
The two played out to an entertaining 2-2 draw in the first leg and both teams have a fair chance of progressing to the next round.
In their nine home games against Portuguese clubs, Arsenal have lost just once in all European competitions (W7 D1) back in the 1991-92 European Cup last 16 encounters against Benfica in a 1-3 defeat to Benfica.
Sporting are winless in their last nine away games against English sides in major European competition (D4 L5).
The Gunners are without a win in their last three UEFA Europa League knockout stage games at home (D2 L1).
Both Arsenal and Sporting CP have a record of four victories and one draw in their last five games.
BETTING TIP: Try a double chance for either team to win and both to score. (12&GG)
ODDS: 3.10
Freiburg Vs Juventus
Following their elimination from the UEFA Champions League, the Europa League could act as a form of compensation for Juventus.
After a narrow 1-0 victory in the first leg, Juventus will be eager to put the tie to bed and progress.
Freiburg have struggled to find form, with a record of two victories and two draws, and one loss in their last five games.
The Old Lady, on the other hand, has four victories and one loss in their last five games.
This encounter will be the second-ever meeting between Juventus and Freiburg in European competition.
It is also Freiburg’s first home match against Juventus or any other Italian side in European competition.
Juventus have lost just one of their last nine European matches against German teams (W5 D3) while SC Freiburg have never lost the second leg of a major European knockout tie (W2 D2), and that record should serve as motivation.
BETTING TIP: Direct win for Juventus.
ODDS: 2.45
Real Betis Vs Manchester United
Erik Ten Hag’s men were quick to put their 7-0 humiliation against Liverpool behind them with a resounding 4-1 victory over Real Betis in the Europa League first leg of the knockout stage.
The Red Devils will head into this decider after drawing 0-0 with Southampton over the weekend.
This is Real Betis’ first home European game against an English side since November 2005 and will need to score four unanswered goals to progress to the next round.
Betis have only progressed from one of their previous six major European ties when they lost the first leg.
They have now gone three games without a victory drawing twice while losing once, they have only won once in their last five games.
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Manchester United have 3 three victories and one draw and loss in their last five games.
Who will win or will the game end in a stalemate?
BETTING TIP: Manchester United to win and 0-3 goals in the match.
ODDS: 2.90